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R&D Projects


Current projects and projects in preparation
R&D PROJECTS
    • ‘New sources for protein-rich food additives’ (‘Protein nutrient extract’).
Top sector Life Sciences and Health, province South Holland, 2018
    • ‘Stable isotope labelled metabolites and cell substrates as markers for diagnostics’.
Top sector Life Sciences and Health, province South Holland, 2017 
    • ‘Understanding of resistence and delivery of drugs: added value of uniform stable-isotope labelled proteins and metaboilites in combination with mass spectrometry.”
(‘Protein labelling for drug delivery’), 
Top sector Life Sciences and Health, province South Holland, 2016
    • ‘ Uniform stable -sotope labelled standards for quntification in mass spectrometry’. 
  NWO-KIEM, Erasmus MC Rotterdam and PLI Leiden, 2015
    • ‘Algae-based platform for new anti-inflamatory agents’, PLI and CURAX, 
 Penvoerder Biofarmind, ‘Innovatie Prestatie Contracten’ (IPC), 2011-2012
    • Facility Sharing in Life Science, FASILIAS knowledge voucher. 
Alphabet Business College/CART GIGA facility University of Liege, 2010
    • ‘Cost-effective production of glyconutrients: exploration of optimal source-production method’, Agentschap NL, 2009
    • ‘Exploration of biodiversity of microorganisms for production of specific food and health bioactive molecules and rapid assessment by means of FT-IR’, SenterNovem, Tender Food and Nutrition Delta Fase 2. FND-MKB Innovation project PLI-PRISNA, 2008-2009
    • ‘New approach for discovery and development of functional foods: the metabolomics
                                        Quantification Tool (MQT)’, (in collaboration with Prof. T. Hankemeier, LACDR,
                                        Leiden, SenterNovem, Tender Food and Nutrition Delta Fase 2, 2007-2008
    • ‘Exploration of biodiversity of microorganisms for production of specific food and health bioactive molecules and rapid assessment by means of FT-IR’, (in collaboration with Prof. De Grip, RUNMC, Nijmegen). SenterNovem, Tender Food and Nutrition Delta Fase 2, 2007
    • ‘Commercialization of ligand-protein interaction studies for characterization of ligand
                                        specificity’. STW phase 1. Valorisation grant to Dr. T. Egorova-Zachernyuk/PLI, Leiden, 2005
    • ‘Speeding up drug discovery via large scale membrane protein production and stable isotope labelling’ (partner RUNMC) SenterNovem ,‘Technologische samenwerking’, 2004
    • ‘Protein labelling for drug discovery and drug design’, phase II.
 Award from STIGON, special program for stimulation of innovative drug discovery and
                                         entrepreneurship in the Netherlands to Dr. T. Egorova-Zachernyuk, 2003-2005
    • ‘Protein labelling for drug discovery and drug design’, phase I.
                                        Award from STIGON, special program for stimulation of innovative drug discovery and entrepreneurship in the Netherlands to Dr. T. Egorova-Zachernyuk, 2002-2003
    • Business plan ‘Protein labelling for drug discovery and drug design’, 
Prize New Venture 2001 to Dr. T.A. Egorova-Zachernyuk (PLI, Leiden), top 10 first and second round, 2001


PROJECTS in preparation
    • ’From biodiverse source to high-value products: cost-effective and sustainable bioprocessing of food grade ingredients’.
    • ‘Sustainability of natural biodiversity in the Netherlands via monitoring of natural features’.
    • ‘Development of specific ingredients for modulation of gastro-intestinal health’.


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